Sitemap - 2026 - Derek Thompson

Is This the End of Booze?

America, 1926: What a Forgotten 100-Year-Old Report Says About Who We Are

It’s the Best Time Ever to Become a Millionaire by Working Alone

The U.S. Went to War to Take Away Iran's Superweapon. It Gave Iran a New One.

The Derek Thompson Substack Turns 1! Here's How the Newsletter Is Doing

The Cult of the Enhanced Self

Why Do the Best Leaders Fail at the Most Important Job?

Why Are Men So Bad at Making—and Keeping—Friends?

The AI Boom Has Entered Its 'Wait, Is This Worth It?' Era

Can America Escape the Cycle of Vicemaxxing?

The Global Fertility Crisis Is Worse Than You Probably Think

The Six Megatrends That Define 2026

How AI Could Help Cure Pancreatic Cancer

The Big Question Lurking Beneath the AI Debate

Why Your Best Ideas Aren’t Original

How American Dads Became the Parents Their Fathers Never Were

If America's So Rich, How'd It Get So Sad?

The AI Vibe Shift Has Officially Arrived

How ‘Zombie Flow’ Took Over Culture

The Substack-ification of American Religion

Why 'Cost Disease' Is the Secret Force Behind America's Toxic Solitude

Is the Smartphone Theory of Everything Wrong? A Comprehensive Investigation

What Is Anthropic Thinking?

We Haven’t Seen the Worst of What Gambling and Prediction Markets Will Do to America

‘Yes, AI Is a Bubble. There Is No Question.’

The Most Important Chart in AI Is Also the Most Misunderstood

Why Can't People Agree on a Shared Set of Facts?

This War's Economic Crisis Could Get Much Worse—For the U.S. and the Whole World

The Economic Crisis of the Iran War Could Get Very Bad, Very Fast

On Being a Dad

How Metrics Make Us Miserable

Why AI Is 'Not Particularly Good' at Curing Disease (Plus: The Next GLP-1 Boom and Why America Hates Big Pharma)

Nobody Knows Anything

The Obscure Media Theory That Explains '99% of Everything'

The Doomsday Scenario for AI and Jobs

The 11 Most Interesting Ideas I Read on Paternity Leave